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Retatrutide acetate, also known as LY3437943, is a triple agonist peptide that targets the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). It demonstrates high efficacy with EC50 values of 5.79 nM for human GCGR, 0.0643 nM for human GIPR, and 0.775 nM for human GLP-1R. In murine models, it shows EC50 values of 2.32 nM for GCGR, 0.191 nM for GIPR, and 0.794 nM for GLP-1R.
This peptide is supplied as a white lyophilized powder in sealed vials, ensuring stability and ease of use for laboratory settings. It is designed for research applications, particularly in studies related to weight management, glucose tolerance, and energy expenditure. Retatrutide acetate engages GCGR to enhance glucose tolerance and promotes significant weight reduction through increased energy expenditure, making it a valuable compound for obesity research.
Our product is manufactured under strict quality controls to guarantee consistency and reliability. It is available in various concentrations to meet diverse research needs, and we support bulk orders and custom packaging options. For researchers seeking semaglutide to buy or similar peptides, Retatrutide offers a potent alternative with triple receptor agonism.
Handling and storage recommendations include storing the lyophilized powder at 2-8°C in a dry environment. For long-term preservation, keeping it at -20°C or -80°C in a sealed container with desiccant is advised to prevent degradation. This product is intended solely for scientific research and not for human consumption.
