Account
Inquiry
Semaglutide is a synthetic simple peptide belonging to the glucagon-like peptide-1 (GLP-1) receptor agonist class. This 31-amino acid polypeptide features structural modifications that enhance its stability and biological activity compared to natural GLP-1.
The simple peptides structure of semaglutide includes two key modifications: replacement of glycine with 2-aminoisobutyric acid at position 2, and attachment of an 18-carbon fatty acid chain via PEG spacer to lysine at position 26. These modifications provide resistance to DPP-4 degradation and prolonged half-life through albumin binding.
As one of the most effective simple peptides in the GLP-1 agonist class, semaglutide demonstrates multiple pharmacological actions including glucose-dependent insulin secretion, glucagon suppression, delayed gastric emptying, and reduced appetite. These properties make it valuable for research in type 2 diabetes and obesity.
Our simple peptides semaglutide is supplied as lyophilized white powder in sterile vials with the following specifications:
