High Purity 99.0% Cagrilintide CAS 1415456-99-3 for Obesity Research | Pharmaceutical Peptide

We’ve been getting more requests for this one lately, mostly from labs pushing into obesity and metabolic disorder work, and it’s pretty much the same story every time — they need something that hits both the amylin and calcitonin receptors without the usual degradation issues, and that’s where this long-acting acylated analogue comes in, though the lead time can stretch to 20 days or so if we’re out of stock on the raw peptide.

It’s a white to off-white powder under normal light, but what you really care about is that HPLC purity at ≥98.0% with single impurities capped at ≤2.0%, which is tighter than most generic batches we’ve seen, and the acetate content runs between 5.0% and 12.0% — we usually have COA data for that, but confirm if you need a specific range for your formulation because some protocols get finicky about acetate levels.

The molecular weight comes in at 4409.1 g/mol, and teh sequence runs γ-Glu-Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Glu-Phe-Leu-Arg-His-Ser-Ser-Asn-Asn-Phe-Gly-Pro-Ile-Leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Pro-NH2 with that disulfide bridge at Cys4-Cys9, but honestly, most buyers just check the CAS — 1415456-99-3 — and move on, though we do have the full sequence data if you need to verify it against your internal standdard.

Storage is straightforward but non-negotiable: -20°C, protected form light, and we’ve seen that if you let it sit at room temp for more than a few hours, the peptide content — which is ≥80.0% by the way — starts dropping, so it’s not something you want to leave on the bench overnight, and the water content needs to stay at ≤10.0% to avoid hydrolysis issues.

One thing a lot of people don’t think to ask is that this isn’t really suited for cell-based assays unless you’re running them in serum-free conditions, because the acetate buffer can interfere with some receptor-binding studies, but for in vivo work in rodent models of obesity, it’s been performing well — we’ve seen labs pair it with a GLP-1 agonist for effects, though that’s definately beyond our scope for recommending.

When you order, you’ll get a sealed vial with the powder under argon, a COA with HPLC traces and peptide content data, and an SDS if you request it — we usually have stock for the 10mg or 25mg sizes, but the 50mg requires a lead time check since we don’t always run that batch unless there’s demand.