Account
Inquiry
Retatrutide (LY3437943) acetate is a triple agonist peptide designed for research use, targeting the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). It exhibits high inhibitory activity with EC50 values of 5.79 nM for human GCGR, 0.0643 nM for human GIPR, and 0.775 nM for human GLP-1R. In mouse models, the EC50 values are 2.32 nM for GCGR, 0.191 nM for GIPR, and 0.794 nM for GLP-1R.
In vivo studies demonstrate that Retatrutide acetate engages with GCGR to enhance glucose tolerance through GIP or GLP-1 receptor pathways. Activation via the glucagon receptor results in significant weight reduction and increased energy expenditure, making it a valuable compound for obesity research. This product is strictly for research purposes and not intended for personal use.
For those exploring where to buy semaglutide UK, our Retatrutide offers a high-purity alternative with similar research applications. It is supplied as a lyophilized powder with a shelf life of 2 years when stored under refrigeration, kept dry, and protected from light.
Our product is available in various packaging options, including 10mg, 15mg, and 20mg vials, typically packaged in boxes of 10 vials. The price is valid until October 31, 2025, ensuring long-term availability for research institutions. This makes it a reliable choice for bulk orders and customized research needs, similar to inquiries about where to buy semaglutide UK.
