Running a study on mitochondrial uncoupling and oxidative stress simultaneously? You can waste budget buying three separate vials from different suppilers with varying purity specs—or you can grab one vial that we’ve already co-lyophilized to ≥99.5%. Most buyers go with the 5mg vial for acute dosing experiments, but it’s actually the 2mg that gives you finer titration in micro-infusion work. We usually have stock on the 10mg vials too, but check lead time if you need more than 200 units. The peptide itself is filter sterilized at <0.1 EU/mg endotoxin—pretty much negligible for most cell-based assays.
The glutathione fraction runs C10H17N3O6S at 307.32 g/mol, and it’s the reduced form (GSH), not the oxidized GSSG you’d get form cheaper blends—saves you the extra HPLC pass to verify activity. Solubility is immediate in water or saline, so you’re not sitting there vortexing for five minutes. We do 2mg, 5mg, and 10mg vials (though I’d skip teh 2mg if you’re running a large cohort, because you’ll just burn through packaging). Storage is 2-8°C in a dry cabinet; moisture pickup messes with MOTS-C stability, and we’ve seen that happen in humid labs after 30 days or so.
It’s a combination of three actives, so you obviously can’t isolate individual contributions in your curve unless you run a separate control. That’s not a flaw—it’s just a reality for anyone trying to measure pathway-specific effects. For general metabolic reprogramming or senescence studies, though, the actually beats running them sequentially. One thing no one thinks to ask: the lyophilized cake can crack if you rehydrate too fast with cold saline—slow injection along the vial wall avoids losing matrial. Also, this won’t work for oral dosing or anything involving serum stability beyond 4 hours at 37°C—the MOTS-C linear sequence degrades in plasma without a D-form countermeasure.
Batch-to-batch variation is tighter than most ISO9001-compliant outfits because we run a separate MS check on every reconstituted aliquot weship. Custom packging for research quantities takes about a week and you specify the vial size. Anyway, the MOQ is three vials.
We can do as few as 10 vials for the 2mg size, but if you need a custom quantity, just reach out and we'll work it out.
Standard lead time is 3-5 business days for in-stock items, including the 10mg vials. Bulk custom orders may take a bit longer.
Yes, we include a certificate of analysis and ISO9001 compliance docs with every order. Just request it when you place the order.
Keep it in the fridge at 2-8°C in a dry spot. Don't freeze it, and make sure the vial stays sealed until you're ready to reconstitute.
Absolutely, we offer customization for research quantities. Just tell us the vial size and amount you need, and we'll price it out for you.