Amble Tirzepatide (LY3437943) acetate is a triple agonist peptide targeting glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). This high purity compound demonstrates potent activity with EC50 values of 5.79 nM (hGCGR), 0.0643 nM (hGIPR), and 0.775 nM (hGLP-1R).
The Amble Tirzepatide peptide formulation shows significant effects on glucose tolerance enhancement through GIP or GLP-1 receptor pathways. Its activation via glucagon receptor leads to notable weight reduction and increased energy expenditure, making it valuable for obesity-related research applications.
Our Amble Tirzepatide is supplied as lyophilized powder in pharmaceutical grade purity (>99%), available in convenient 10mg, 30mg or 60mg vials. The product is strictly for research use only, not intended for human consumption.