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We've been getting inconsistent results from the standard GLP-1 analogues we were sourcing, batch-to-batch variability was eating into our timelines, so I ordered this Arg34GLP-1(9-37) intermediate to tighten up the synthesis work for the GLP-1 receptor binding assays where we need a clean starting point.
The ≥99% purity by HPLC is the main reason I went with this—most supliers hover around 97-98% and you can see the difference in the, especially when you're working at low nanomolar concentrations where every impurity throws off the signal.
Storage is -20°C protected form light, which is standard for this class of peptides, but what I didn't expect was the powder being soluble in water and DMSO with no noticeable residue—that actually saves us a centrifugation step we usually have to do with the cheaper stuff.
Molecular weight is 338.36 g/mol and the CAS is 1169630-82-3, so it matches what we need for patent work, and we'll probably request a COA on the first batch to confirm the HPLC trace before scaling up the order.
Lead time was about 10 business days for the 5g vial we got, though they mentioned customized packaging is avaliable if we need different gram sizes or vials for the long-term storage—we usually have stock of the 100mg vials, but confirm lead time for teh larger quantities.
It's not suited for anything involving in vivo work since it's research use only, and the -20°C requrement means you'll need a dedicated freezer if you're ordering more than a couple vials at a time—basically, it's a solid intermediate for early-stage work but don't expect it to handle like a finished drug substance.
