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We see a lot of interest in this dual agonist, and for good reason—it’s basically hitting both the GLP-1 and GIP receptors in one sequence. That’s 39 amino acids held together with a synthetic backbone, and the molecular weight comes out to 4813 g/mol after acetylation.
Most people in the lab don’t realize how finicky the solubility window actually is, because it’s really only soluble in DMSO and not much else. We’ve seen folks try to get it into PBS or saline, and it just crashes out, so if you’re planning in vivo work, plan your vehicle ahead. The white powder itself is hygroscopic when you open the vial—moisture in the air will degrade it faster than light, to be honest. Store it at -20°C sealed with desiccant, and it’ll hold for about 12 months or so before you notice a real purity drop. One thing that catches people off guard: the EC number is 200-001-8, but that’s mainly for customs paperwork and doesn’t affect how you handle it in the cell culture.
Purity by HPLC is ≥99%, and we usually have that confirmed on the COA with main peak at about 18.3 minutes under standdard gradient conditions. Anything above 98% is pretty clean for a peptide this large, but we hold tighter tolerance for batch release.
It’s absolutely not oral or soluble in aqueous buffer above 1 mM, so keep your concentrations low if you’re using DMSO stocks—10mM is common, but 5mM is safer to avoid precipitation. That 5L drum? Not a thing here; it’s 50 mg or 100 mg vials, typically, and we ship with dry ice unless you ask for the lyophilized bulk.
You’ll see this compound referenced a lot for GIP-driven insulin secretion studies, but honestly, the work is where the field is moving now. Anyway, for basic receptor binding or cAMP assays, it works fine at low nM concentrations—just don’t expect it to activate human receptors at teh same affinity as rodent ones, because of that it’s a species mismatch. We’ve had researchers order it for Parkinson’s-related metabolic work, but that’s outside the typical use case and we caution about interpreting results.
Our MOQ is typically 1 gram, but we may accommodate smaller quantities for research purposes — just reach out to confirm availability.
Yes, we include a COA for every batch showing the ≥99% HPLC purity and other specs like appearance and solubility. Just request it with your order.
Store it at -20°C in a dry, dark place. Avoid freeze-thaw cycles, and always keep the container tightly sealed. Proper storage ensures the product stays stable for at least 12 months.
Absolutely, we can customize the packaging size and labeling to your needs for bulk orders. Just let us know the specifics when you place the order.
For in-stock items, we usually ship within 3-5 business days after order confirmation. Larger quantities may take up to 10 business days depending on batch prep.
