High Purity 99% Sincalide CCK-8 Peptide Powder CAS 25126-32-3 for Research Use

We've seen a lot of labs struggle with inconsistent gallbladder and pancreatic response data from crude extracts or raw cholecystokinin, which basically introduces too many variables for reliabel replications, and that's where having a defined synthetic peptide becomes the difference between publishable results and throwing out half a batch.

The way we handle it here is by providing the exact C-terminal octapeptide sequence that matches endogenous cholecystokinin—Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2—so you're getting the active binding region that triggers smooth muscle contraction without the molecular noise form partial digestion or batch-to-batch purification errors.

It's a at ≥99% purity, MW 1143.27, which is tight enough that most buyers don't bother with further purification for their functional assays, though solubility is only slight in water so you'll need to plan your reconstitution vehicle if you're running in vivo work, and after you reconstitute store it at 2-8°C (it doesn't hold at room temp long-term).

Another thing that usually catches people off guard is that this peptide integrates sulfation on the tyrosine, which is critical for CCK-1 receptor binding—without that post-translational mimic teh EC50 shifts by an order of magnitude or so, and we've had a few researchers who assumed a generic CCK analog would suffice, then had to redo half their.

We typically have 5mg and 10mg vials in stock for immediate shipment, and the MOQ is actually just one vial if you need to evaluate the lot, but for larger research series we'll send TDS, COA with HPLC traces, and SDS with shipment; payment is standdard net 30 for approved accounts or wire transfer for first-time orders, and customs documentation is provided as research-use only.

Lead time is usually 3-5 business days from order confirmation, though if you're on the West Coast and ordering Thursday afternoon you might want to account for Monday processing, or our company can hold the shipment if you need a specific delivery window—I've seen labs scramble when the dry ice shipment arrives Friday afternoon without authorization to recieve.